General Information of Drug Metabolite (DM) (ID: DM018631)
DM Name
Naloxone Metabolite M7
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040 Unclear - Unclear Naloxone [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Naloxone DR1127 Approved Opiate dependence
References
1 Optimization of Mass Spectrometry Imaging for Drug Metabolism and Distribution Studies in the Zebrafish Larvae Model: A Case Study with the Opioid Antagonist Naloxone
2 PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5'-Diphospho-glucuronosyltransferase Substrates

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