| General Information of Drug Metabolite (DM) (ID: DM019139) |
| DM Name |
Tivantinib Metabolite M8 precursor
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Alcohol dehydrogenase class-II (ADH4)
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DME0130
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| Unclear - Unclear |
Tivantinib
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Tivantinib |
DR3448
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Phase 3 |
Solid tumour/cancer |
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| References |
| 1 |
Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib
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