| General Information of Drug Metabolite (DM) (ID: DM019568) |
| DM Name |
PD-153035 M3
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D (CYP2D)
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DMEN826
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| Oxidation - O-demethylation |
PD-153035
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[1] |
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Cytochrome P450 3A (CYP3A)
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DMEN065
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| Oxidation - O-demethylation |
PD-153035
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| PD-153035 |
DR2901
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Discontinued in Phase 1 |
Psoriasis vulgaris |
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| References |
| 1 |
Metabolism of epidermal growth factor receptor targeting probe [11C]PD153035: impact on biodistribution and tumor uptake in rats
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