| General Information of Drug Metabolite (DM) (ID: DM019706) |
| DM Name |
AZD8931 M12
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - O-desmethylation |
AZD8931
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Conjugation - Glucuronidation |
AZD8931
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| AZD8931 |
DR3226
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Phase 2 |
Breast cancer |
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| References |
| 1 |
Metabolic disposition of AZD8931, an oral equipotent inhibitor of EGFR, HER2 and HER3 signalling, in rat, dog and man
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