Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM000011)
DM Name	Tamoxifen glucuronides

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
UDP-glucuronosyltransferase 1A10 (UGT1A10)	DME0075	Endoxifen	Conjugation - Glucuronidation	Tamoxifen citrate	[1]
UDP-glucuronosyltransferase 1A10 (UGT1A10)	DME0075	4-hydroxytamoxifen	Conjugation - Glucuronidation	Tamoxifen citrate	[1]
UDP-glucuronosyltransferase 1A8 (UGT1A8)	DME0064	Endoxifen	Conjugation - Glucuronidation	Tamoxifen citrate	[1]
UDP-glucuronosyltransferase 1A8 (UGT1A8)	DME0064	4-hydroxytamoxifen	Conjugation - Glucuronidation	Tamoxifen citrate	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Tamoxifen citrate		DR1529	Approved		Breast cancer

References
1	PharmGKB:Tamoxifen citrate

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