| General Information of Drug Metabolite (DM) (ID: DM000194) |
| DM Name |
Fluconazole O-Glucuronidated metabolite
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - Glucuronidation |
Fluconazole
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Fluconazole |
DR0704
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Approved |
Candidiasis |
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| References |
| 1 |
The disposition and metabolism of [14C]fluconazole in humans Drug Metab Dispos. 1991 Jul-Aug;19(4):764-7.
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| 2 |
Investigation into UDP-glucuronosyltransferase (UGT) enzyme kinetics of imidazole- and triazole-containing antifungal drugs in human liver microsomes and recombinant UGT enzymes. Drug Metab Dispos. 2010 Jun;38(6):923-9.
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