Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM000575)
DM Name	Eltrombopag olamine glucuronide conjugate

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
UDP-glucuronosyltransferase 1A1 (UGT1A1)	DME0004	Eltrombopag olamine	Conjugation - Glucuronidation	Eltrombopag olamine	[1]
UDP-glucuronosyltransferase 1A3 (UGT1A3)	DME0041	Eltrombopag olamine	Conjugation - Glucuronidation	Eltrombopag olamine	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Eltrombopag olamine		DR0569	Approved		Thrombocytopenia

References
1	Eltrombopag for use in children with immune thrombocytopenia. Blood Adv. 2018 Feb 27;2(4):454-461.

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