| General Information of Drug Metabolite (DM) (ID: DM000651) |
| DM Name |
Aprepitant glucuronide
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A4 (UGT1A4)
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DME0048
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| Conjugation - Glucuronidation |
Aprepitant
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Aprepitant |
DR0125
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Approved |
Functional nausea/vomiting |
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| References |
| 1 |
In vitro glucuronidation of aprepitant: a moderate inhibitor of UGT2B7 Xenobiotica. 2015;45(11):990-8. doi: 10.3109/00498254.2015.1038743.
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