| General Information of Drug Metabolite (DM) (ID: DM000685) |
| DM Name |
S,S-threo-4'-hydroxy-hydrobupropion
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Aflatoxin B1 aldehyde reductase member 3 (AKR7A3)
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DMEN017
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| Reduction - Ketoreduction |
Bupropion
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[1] |
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Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1)
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DME0199
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| Reduction - Ketoreduction |
Bupropion
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[1] |
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Mephenytoin 4-hydroxylase (CYP2C19)
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DME0021
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| Oxidation - 4'-Hydroxylation |
Bupropion
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Bupropion |
DR0247
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Approved |
Nicotine dependence |
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| References |
| 1 |
DrugBank(Pharmacology-Metabolism)Bupropion
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