| General Information of Drug Metabolite (DM) (ID: DM000985) |
| DM Name |
Deacyl indomethacin glucuronide
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Unclear - Unclear |
Acemetacin
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[1] |
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UDP-glucuronyltransferase (UGT)
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DMEN064
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| Conjugation - Glucuronidation |
Indomethacin
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[2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Indomethacin |
DR0875
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Approved |
Rheumatoid arthritis |
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| Acemetacin |
DR0035
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Phase 4 |
Osteoarthritis |
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| References |
| 1 |
DrugBank(Pharmacology-Metabolism)Acemetacin
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| 2 |
Comparative in vitro metabolism of phospho-tyrosol-indomethacin by mice, rats and humans Biochem Pharmacol. 2013 Apr 15;85(8):1195-202. doi: 10.1016/j.bcp.2013.01.031.
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