| General Information of Drug Metabolite (DM) (ID: DM000993) |
| DM Name |
Irbesartan derivative M7
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Oxidation - Hydroxylation |
Irbesartan
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[1] , [2] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Oxidation - Hydroxylation |
Irbesartan
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[2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Irbesartan |
DR0879
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Approved |
Essential hypertension |
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| References |
| 1 |
Biotransformation of irbesartan in man Drug Metab Dispos. 1998 May;26(5):408-17.
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| 2 |
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
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