| General Information of Drug Metabolite (DM) (ID: DM001275) |
| DM Name |
O-debenzylated safinamide
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Dealkylation |
Safinamide mesylate
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Safinamide mesylate |
DR1456
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Approved |
Parkinsonism |
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| References |
| 1 |
Disposition and metabolism of safinamide, a novel drug for Parkinson's disease, in healthy male volunteers. Pharmacology. 2013;92(3-4):207-16.
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| 2 |
DailyMed : Safinamide mesylate
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