| General Information of Drug Metabolite (DM) (ID: DM001484) |
| DM Name |
Bromfenac glucuronide intemediate
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
UDP-glucuronosyltransferase 1A4 (UGT1A4)
|
DME0048
|
| Unclear - Unclear |
Bromfenac
|
[1] , [2] |
|
UDP-glucuronosyltransferase 2B7 (UGT2B7)
|
DME0040
|
| Unclear - Unclear |
Bromfenac
|
[1] , [2] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Bromfenac |
DR1765
|
Approved |
Cataract |
|
|
| References |
| 1 |
Metabolite profiling and reaction phenotyping for the in vitro assessment of the bioactivation of bromfenac. Chem Res Toxicol. 2020 Jan 21;33(1):249-257.
|
| 2 |
Metabolic disposition of 14C-bromfenac in healthy male volunteers J Clin Pharmacol. 1998 Aug;38(8):744-52. doi: 10.1002/j.1552-4604.1998.tb04815.x.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
