Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM001798)
DM Name	Cevimeline cis-sulfoxidation

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 2D6 (CYP2D6)	DME0009	Cevimeline hydrochloride	Oxidation - Sulfoxidation	Cevimeline hydrochloride	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Cevimeline hydrochloride		DR0294	Approved		Sjogren syndrome

References
1	Identification of human drug-metabolizing enzymes involved in the metabolism of SNI-2011. Biol Pharm Bull. 2001 Nov;24(11):1263-6.

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