Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM002048)
DM Name	Fluvoxamino alcohol
Structure
Structure	3D MOL			2D MOL

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 1A2 (CYP1A2)	DME0003	Fluvoxamine maleate	Oxidation - O-Dealkylation	Fluvoxamine maleate	[1]
Cytochrome P450 1A2 (CYP1A2)	DME0003	Fluvoxamine	Unclear - Unclear	Fluvoxamine	[1]
Cytochrome P450 2D6 (CYP2D6)	DME0009	Fluvoxamine maleate	Oxidation - O-Dealkylation	Fluvoxamine maleate	[1]
Cytochrome P450 2D6 (CYP2D6)	DME0009	Fluvoxamine	Unclear - Unclear	Fluvoxamine	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Fluvoxamine maleate		DR0740	Approved		Obsessive-compulsive disorder

Fluvoxamine		DR5483	Approved		Depression

References
1	Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.

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