| General Information of Drug Metabolite (DM) (ID: DM003157) |
| DM Name |
4,5-dehydrocibenzoline
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Hydrolyzationn |
Cibenzoline
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Cibenzoline |
DR0318
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Phase 4 |
Atrial fibrillation |
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| References |
| 1 |
Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A. Drug Metab Dispos. 2000 Sep;28(9):1128-34.
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