| General Information of Drug Metabolite (DM) (ID: DM003274) |
| DM Name |
4-HPR glucuronide
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A1 (UGT1A1)
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DME0004
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| Unclear - Unclear |
LAU-7b
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[1] |
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UDP-glucuronosyltransferase 1A3 (UGT1A3)
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DME0041
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| Unclear - Unclear |
LAU-7b
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[1] |
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UDP-glucuronosyltransferase 1A6 (UGT1A6)
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DME0072
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| Unclear - Unclear |
LAU-7b
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| LAU-7b |
DR1893
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Phase 3 |
Macular degeneration |
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| References |
| 1 |
Characterization of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP-glucuronosyltransferases. Br J Pharmacol. 2011 Feb;162(4):989-99.
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