| General Information of Drug Metabolite (DM) (ID: DM003328) |
| DM Name |
MK-0859 Metabolite M1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - O-demethylation |
MK-0859
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| MK-0859 |
DR1884
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Phase 3 |
Atherosclerosis |
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| References |
| 1 |
Metabolism and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in humans. Drug Metab Dispos. 2010 Mar;38(3):474-83.
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