| General Information of Drug Metabolite (DM) (ID: DM004081) |
| DM Name |
Oxoglutarate Metabolite C2
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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human thiamin diphosphate (ThDP)-dependent enzyme 2-oxoadipate dehydrogenase (hE1a)
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DMEN205
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| Oxidation - Oxidationn |
Oxoglutarate
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Oxoglutarate |
DR2059
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Investigative |
Discovery agent |
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| References |
| 1 |
The mitochondrial 2-oxoadipate and 2-oxoglutarate dehydrogenase complexes share their E2 and E3 components for their function and both generate reactive oxygen species
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