| General Information of Drug Metabolite (DM) (ID: DM004239) |
| DM Name |
ICYS
|
| Structure |
|
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3D MOL is unavailable
|
2D MOL is unavailable
|
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Dehydropeptidase-I (DPEP1)
|
DME0117
|
| Unclear - Unclear |
Ibrutinib
|
[1] |
|
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
|
N-Acetyl transferases (NATF)
|
DMEN228
|
| Unclear - Unclear |
Ibrutinib
|
[1] |
|
UDP-glucuronosyltransferase 1A1 (UGT1A1)
|
DME0004
|
| Unclear - Unclear |
Ibrutinib
|
[1] |
|
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|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Ibrutinib |
DR0843
|
Approved |
Mantle cell lymphoma |
|
|
| References |
| 1 |
Extrahepatic metabolism of ibrutinib
|
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