Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM004279)
DM Name	Idelalisib Metabolite M19

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 2C9 (CYP2C9)	DME0019	GS-563117	Unclear - Unclear	Idelalisib	[1]
Cytochrome P450 2D6 (CYP2D6)	DME0009	GS-563117	Unclear - Unclear	Idelalisib	[1]
Mephenytoin 4-hydroxylase (CYP2C19)	DME0021	GS-563117	Unclear - Unclear	Idelalisib	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Idelalisib		DR0854	Approved		Chronic lymphocytic leukaemia

References
1	Identification of Novel Pathways in Idelalisib Metabolism and Bioactivation

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