Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM004779)
DM Name	Hydroxynorephedrine

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Dopamine-beta-oxidase (DBO)	DMEN741	Hydroxyamphetamine Hydrobromide	Oxidation - Beta-hydroxylation	Hydroxyamphetamine Hydrobromide	[1] , [2]
dopamine-beta-oxidase (DOB)	DMEN244	Hydroxyamphetamine	Oxidation - Beta-hydroxylation	Hydroxyamphetamine	[2]

Full List of Drug(s) That Produce This DM By Metabolism
Hydroxyamphetamine Hydrobromide		DR5482	Approved		Horner syndrome

Hydroxyamphetamine		DR1770	Approved		Horner syndrome

References
1	Urinary metabolites of p-hydroxyamphetamine in man, rat and guinea-pig
2	Dopamine-beta-oxidase activity in man, using hydroxyamphetamine as substrate

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