| General Information of Drug Metabolite (DM) (ID: DM005475) |
| DM Name |
Hydroxy-Mequitazine
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - Hydrolyzationn |
Mequitazine
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Mequitazine |
DR1030
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Investigative |
Allergic rhinitis |
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| References |
| 1 |
Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes. J Pharmacol Exp Ther. 1998 Feb;284(2):437-42.
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