| General Information of Drug Metabolite (DM) (ID: DM006439) |
| DM Name |
HydroxylLoteprednol
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Serum paraoxonase/arylesterase 1 (PON1)
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DME0169
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| Hydrolysis - Hydrolysis |
Loteprednol etabonate
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Serum paraoxonase/arylesterase 1 (PON1)
|
DME0169
|
| Hydrolysis - Hydrolysis |
Loteprednol etabonate
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Loteprednol etabonate |
DR0985
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Approved |
Conjunctivitis |
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| References |
| 1 |
Identification of esterase involved in the metabolism of two corticosteroid soft drugs. Biochem Pharmacol. 2017 Mar 1;127:82-89.
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