| General Information of Drug Metabolite (DM) (ID: DM007004) |
| DM Name |
Licofelone acyl glucuronide (M1)
|
| Structure |
|
|
3D MOL is unavailable
|
2D MOL is unavailable
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
UDP-glucuronosyltransferase 1A3 (UGT1A3)
|
DME0041
|
| Conjugation - Acyl glucuronidation |
ML-3000
|
[1] |
|
UDP-glucuronosyltransferase 1A9 (UGT1A9)
|
DME0042
|
| Conjugation - Acyl glucuronidation |
ML-3000
|
[1] |
|
UDP-glucuronosyltransferase 2B7 (UGT2B7)
|
DME0040
|
| Conjugation - Acyl glucuronidation |
ML-3000
|
[1] |
|
|
|
|
|
|
|
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 2C8 (CYP2C8)
|
DME0018
|
| Oxidation - Hydrolyzationn |
ML-3000
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| ML-3000 |
DR0951
|
Discontinued |
Osteoarthritis |
|
|
| References |
| 1 |
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
