Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM017443)
DM Name	DP-5439

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 2D6 (CYP2D6)	DME0009	Ripretinib	Unclear - Unclear	Ripretinib	[1]
Cytochrome P450 2E1 (CYP2E1)	DME0013	Ripretinib	Unclear - Unclear	Ripretinib	[1]
Cytochrome P450 3A (CYP3A)	DMEN065	Ripretinib	Unclear - Unclear	Ripretinib	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Ripretinib		DR5952	Approved		Gastrointestinal stromal tumour

References
1	Effects of CYP3A Inhibition, CYP3A Induction, and Gastric Acid Reduction on the Pharmacokinetics of Ripretinib, a Switch Control KIT Tyrosine Kinase Inhibitor

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.