| General Information of Drug Metabolite (DM) (ID: DM017913) |
| DM Name |
Riociguat metabolite M4
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A1 (UGT1A1)
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DME0004
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| Conjugation - N-glucuronidation |
Riociguat
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[1] |
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UDP-glucuronosyltransferase 1A9 (UGT1A9)
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DME0042
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| Conjugation - N-glucuronidation |
Riociguat
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Riociguat |
DR1427
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Approved |
Pulmonary hypertension |
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| References |
| 1 |
Clinical Pharmacokinetic and Pharmacodynamic Profile of Riociguat
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