| General Information of Drug Metabolite (DM) (ID: DM018027) |
| DM Name |
Alpelisib Metabolite M12
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
UDP-glucuronosyltransferase 1A9 (UGT1A9)
|
DME0042
|
| Conjugation - N-Glucuronidation |
Alpelisib
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Alpelisib |
DR0074
|
Approved |
Breast cancer |
|
|
| References |
| 1 |
Absorption, distribution, metabolism, and excretion of [(14)C]BYL719 (alpelisib) in healthy male volunteers. Cancer Chemother Pharmacol. 2015 Oct;76(4):751-60.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
