| General Information of Drug Metabolite (DM) (ID: DM019890) |
| DM Name |
BMS-275183 Metabolite M23
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
BMS-275183
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| BMS-275183 |
DR3224
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Phase 2 |
Solid tumour/cancer |
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| References |
| 1 |
CYP3A4-mediated ester cleavage as the major metabolic pathway of the oral taxane 3'-tert-butyl-3'-N-tert-butyloxycarbonyl-4-deacetyl-3'-dephenyl-3'-N-debenzoyl-4-O-methoxycarbonyl-paclitaxel (BMS-275183)
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