Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM019949)
DM Name	20(OH)D2
Structure
Structure	3D MOL is unavailable			2D MOL is unavailable

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cholesterol desmolase (CYP11A1)	DME0099	Ergocalciferol	Unclear - Unclear	Ergocalciferol	[1]

DME(s) Metabolizing This DM

DME Name	DME ID	Product	Reaction	Related Drug	REF
Calcidiol 1-monooxygenase (CYP27B1)	DME0046	1,20(OH)2D2	Unclear - Unclear	Ergocalciferol	[1]
Cholesterol desmolase (CYP11A1)	DME0099	17,20(OH)2D2	Unclear - Unclear	Ergocalciferol	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Ergocalciferol		DR0596	Approved		Hypoparathyroidism

References
1	The Metabolic Activation of Sofosbuvir Is Impaired in an Experimental Model of NAFLD. Biology (Basel). 2022 Apr 30;11(5):693. doi: 10.3390/biology11050693.

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