Details of the Drug Metabolized by Drug-Metabolizing Enzyme (DME)

General Information of Drug (ID: DR3116)
Drug Name
Guanosine
Synonyms .
Structure
3D MOL 2D MOL
Pharmaceutical Properties Molecular Weight 283.24 Topological Polar Surface Area 155
Heavy Atom Count 20 Rotatable Bond Count 2
Hydrogen Bond Donor Count 5 Hydrogen Bond Acceptor Count 7
Cross-matching ID
PubChem CID
135398635
ChEBI ID
CHEBI:16750
CAS Number
118-00-3
TTD Drug ID
D0H1OL
Formula
C10H13N5O5
Canonical SMILES
C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N=C(NC2=O)N
InChI
InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
InChIKey
NYHBQMYGNKIUIF-UUOKFMHZSA-N
The Metabolic Roadmap of This Drug
The Full List of Drug Metabolites (DM) of This Drug
DM Name DM ID PubChem ID Reaction DM Level REF
Guanine DM003593
135398634
Unclear - Unclear 1 [1]
The Full List of Metabolic Reaction (MR) of This Drug
MR ID Reactant Product MR Type DME REF
MR010385 Guanosine Guanine Unclear - Unclear PNP [1]
Drug-Metabolizing Enzyme(s) (DME) Metabolizing This Drug
DME Name DME Info Species Uniprot ID EC Number REF
Purine nucleoside phosphorylase (PNP) DME0437 Homo sapiens
PNPH_HUMAN
2.4.2.1
[1]
References
1 Neuroprotective Effects of Guanosine in Ischemic Stroke-Small Steps towards Effective Therapy

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