| General Information of Drug (ID:
DR0019) |
| Drug Name |
DACTHF
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| Synonyms |
Deazaacyclotetrahydrofolate; 5-deazaacyclotetrahydrofolate; 5-DACTHF |
| Indication |
Discovery agent
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Investigative
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[1]
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| The Metabolic Roadmap of This Drug |
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| The Full List of Drug Metabolites (DM) of This Drug |
| DM Name |
DM ID |
PubChem ID |
Reaction |
DM Level |
REF |
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Unclear
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DM009999
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N. A. |
Unclear |
1 |
[1]
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| The Full List of Metabolic Reaction (MR) of This Drug |
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| Drug-Metabolizing Enzyme(s) (DME) Metabolizing This Drug |
| DME Name |
DME Info |
Species |
Uniprot ID |
EC Number |
REF |
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Folylpolyglutamate synthase (FPGS)
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DME0191
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Homo sapiens
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[1]
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| References |
| 1 |
Role of folylpolyglutamate synthetase in the metabolism and cytotoxicity of 5-deazaacyclotetrahydrofolate, an anti-purine drug. J Biol Chem. 1994 Apr 1;269(13):9714-20.
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