Details of the Drug Metabolized by Drug-Metabolizing Enzyme (DME)

General Information of Drug (ID: DR0041)
Drug Name
Acetylcholine chloride
Synonyms
Acetilcolina cloruro [DCIT]; Acetylcholine (chloride); Acetylcholine hydrochloride; Acetylcholini chloridum; Acetylcholinium chloride; Arterocoline; Azetylcholinchlorid; Chloroacetylcholine; Choline acetate (ester) chloride; Choline, chloride acetate; MIOCHOL-E; Miochol; O-Acetylcholine chloride; Ovisot; 2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride; 2-Acetoxyethyltrimethylammonium chloride; 60-31-1; Acecholin; Acecoline; Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride; ACETYLCHOLINE CHLORIDE; ACH chloride
Indication Cataract [ICD11: 9B10] Approved [1]
Structure
3D MOL is unavailable 2D MOL
Pharmaceutical Properties Molecular Weight 181.66 Topological Polar Surface Area 26.3
Heavy Atom Count 11 Rotatable Bond Count 4
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 3
Cross-matching ID
PubChem CID
6060
ChEBI ID
CHEBI:2417
CAS Number
60-31-1
TTD Drug ID
D0Q9HF
Formula
C7H16ClNO2
Canonical SMILES
CC(=O)OCC[N+](C)(C)C.[Cl-]
InChI
1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChIKey
JUGOREOARAHOCO-UHFFFAOYSA-M
Drug-Metabolizing Enzyme(s) (DME) Metabolizing This Drug
DME Name DME Info Species Uniprot ID EC Number REF
Acetylcholinesterase (ACHE) DME0058 Homo sapiens
ACES_HUMAN
3.1.1.7
[2]
References
1 Acetylcholine Chloride was approved by FDA. The 2020 official website of the U.S. Food and Drug Administration.
2 How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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