Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000006)
Formula
SVG example
Reactant Abacavir Product 1144U88
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000004 Abacavir 2269W93(Carboxylate) Oxidation - Oxidation Abacavir [1]
MR000005 Abacavir 361W94(glucuronide) Conjugation - Glucuronidation Abacavir [2]
MR000003 Abacavir Abacavir monophosphate Other reaction - Phosphorylation Abacavir [3]
References
1 The metabolic activation of abacavir by human liver cytosol and expressed human alcohol dehydrogenase isozymes Chem Biol Interact. 2002 Nov 10;142(1-2):135-54. doi: 10.1016/s0009-2797(02)00059-5.
2 Product characteristics of Triumeq
3 A review of the pharmacokinetics of abacavir. Clin Pharmacokinet. 2008;47(6):351-71.

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