Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000079)
Formula
XDH
SVG example
Oxidation
Reactant Xanthine Product Uric acid
Reactant Info Product Info
Metabolic Enzyme Xanthine dehydrogenase/oxidase (XDH) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004037 Xanthine Guanine Unclear Xanthine [1]
MR004024 Xanthine XMP Unclear Xanthine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000085 Adenosine-c-phosphate Uric acid Unclear Adenosine-c-phosphate [3]
MR008773 Didanosine Uric acid Unclear - Unclear Didanosine [4]
MR006316 Fructose Uric acid Unclear Fructose [5]
MR007055 Hypoxanthine Uric acid Conjugation - Glucuronidation Hypoxanthine [6]
MR008772 Hypoxanthine Uric acid Unclear - Unclear Didanosine [7]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004032 Uric acid Allantoin Unclear Xanthine [2]
MR007510 Uric acid Allantion Unclear Inosine [8]
References
1 Biosensing methods for xanthine determination: a review
2 Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism
3 Transport and metabolism of N6- and C8-substituted analogs of adenosine 3',5'-cyclic monophosphate and adenosine 3'5'-cyclic phosphorothioate by the isolated perfused rat kidney Life Sci. 1983 Mar 28;32(13):1489-98. doi: 10.1016/0024-3205(83)90915-3.
4 DrugBank(Pharmacology-Metabolism):Didanosine
5 High fructose diet: A risk factor for immune system dysregulation
6 T3DB:Hypoxanthine
7 Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes
8 Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.