Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000157)
Formula
NAT1 ...
SVG example
N-Demethylation
Reactant Alogliptin Product Alogliptin M1
Reactant Info Product Info
Metabolic Enzyme N-acetyltransferase 1 (NAT1) DME Info
N-acetyltransferase 2 (NAT2) DME Info
Metabolic Type Oxidation - N-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000158 Alogliptin Alogliptin M2 Oxidation - Deamination Alogliptin [1]
References
1 An update on the clinical pharmacology of the dipeptidyl peptidase 4 inhibitor alogliptin used for the treatment of type 2 diabetes mellitus. Clin Exp Pharmacol Physiol. 2015 Dec;42(12):1225-38.

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