Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000159)
Formula
SVG example
Phosphorylation; Galactokinase
Reactant Alpha-D-galactose Product Alpha-D-galactose 1-phosphate
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
Metabolic Type Other reaction - Phosphorylation; Galactokinase
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007412 CERC-801 Galactose-1-phosphate Unclear CERC-801 [1]
MR012928 UDP-galactose Galactose-1-phosphate Oxidation - Hydrolyzationn UDP-galactose [2]
MR004472 UDP-galactose Galactose-1-phosphate Unclear UDP-glucose [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012929 Galactose-1-phosphate UDP-galactose Unclear UDP-galactose [3]
MR004473 Galactose-1-phosphate UDP-galactose Unclear UDP-glucose [4]
References
1 Molecular and biochemical characterization of human galactokinase and its small molecule inhibitors. Chem Biol Interact. 2010 Dec 5;188(3):376-85.
2 UDP-galactose hydrolysis in brain and its effect on cerebroside synthesis
3 UDP-galactose 4'-epimerase activities toward UDP-Gal and UDP-GalNAc play different roles in the development of Drosophila melanogaster
4 Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium

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