Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000168)
Formula
SVG example
Reactant Aminophenazone Product Aminophenazone metabolite I
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000169 Aminophenazone 4-(Dimethylamino)-5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one Oxidation - N-Dealkylation Aminophenazone [1]
MR000170 Aminophenazone N-Desmethylaminopyrine Oxidation - N-Dealkylation Aminophenazone [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000166 Aminophenazone metabolite I Aminophenazone Metobolite II Unclear Aminophenazone [3]
References
1 Cytochromes P450: a structure-based summary of biotransformations using representative substrates Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742.
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
3 U. S. FDA Label - Aminophenazone

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