Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR000208)
Formula
	Reactant	Amoxapine		Product	N-Formylamoxapine
	Reactant	Reactant Info		Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000205	Amoxapine	7-hydroxyamoxapine	Oxidation - Hydroxylation	Amoxapine	[1], [2]
MR000206	Amoxapine	8-hydroxyamoxapine	Oxidation - Hydroxylation	Amoxapine	[1], [2]
MR000207	Amoxapine	N-Formyl-7-hydroxyamoxapine	Unclear	Amoxapine	[3]

References
1	Addition of amoxapine improves positive and negative symptoms in a patient with schizophrenia. Ther Adv Psychopharmacol. 2013 Dec;3(6):340-2.
2	DrugBank(Pharmacology-Metabolism)Amoxapine
3	Transformation of amoxapine by Cunninghamella elegans Appl Environ Microbiol. 2000 Aug;66(8):3646-9. doi: 10.1128/AEM.66.8.3646-3649.2000.

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