Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR000234)
Formula	CYP1A2
	Reactant	6,7-dichloro-3-hydroxy-1,5 dihydro-imidazo[2,1-b]quinazolin-2-one		Product	2-amino-5,6-dichloro-3,4,-dihydroquinazoline
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 1A2 (CYP1A2)					DME Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000235	Anagrelide hydrochloride	6,7-dichloro-3-hydroxy-1,5 dihydro-imidazo[2,1-b]quinazolin-2-one	Oxidation - 3-Hydroxylation	Anagrelide hydrochloride	[1]

References
1	Colorimetric detection of human caeruloplasmin oxidase activity after electrophoresis in agar plates or after immunoelectrophoresis. Nature. 1958 Apr 5;181(4614):999-1000. doi: 10.1038/181999b0.

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