Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000275)
Formula Reactant Apremilast metabolite M5 Product Apremilast metabolite M13
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000280 Apremilast Apremilast metabolite M5 Unclear Apremilast [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000273 Apremilast metabolite M5 Apremilast metabolite M19 Hydrolysis - Hydrolysis Apremilast [1]
MR000274 Apremilast metabolite M5 Apremilast metabolite M22 Hydrolysis - Hydrolysis Apremilast [1]
References
1 Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration. Xenobiotica. 2011 Dec;41(12):1063-75.

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