Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000371)
Formula Reactant Binimetinib metabolite M4 Product Binimetinib metabolite M5
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000368 GSH adduct Binimetinib metabolite M4 Unclear Binimetinib [1]
References
1 Binimetinib Is a Potent Reversible and Time-Dependent Inhibitor of Cytochrome P450 1A2 Chem Res Toxicol. 2021 Apr 19;34(4):1169-1174. doi: 10.1021/acs.chemrestox.1c00036.

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