Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000386)
Formula Reactant Asunaprevir metabolite M8 Product Asunaprevir metabolite M11,19,20
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000390 BMS-650032 Asunaprevir metabolite M8 Oxidation - Hydroxylation BMS-650032 [1], [2]
References
1 Effect of CYP3A5*3 genetic variant on the metabolism of direct-acting antivirals in vitro: a different effect on asunaprevir versus daclatasvir and beclabuvir J Hum Genet. 2020 Jan;65(2):143-153. doi: 10.1038/s10038-019-0685-2.
2 DrugBank(Pharmacology-Metabolism)Asunaprevir

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