Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000462)
Formula
SVG example
Reactant Bromfenac Product Bromfenac metabolite M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000461 Bromfenac Bromfenac glucuronide intemediate Unclear Bromfenac [1], [2]
References
1 Metabolite profiling and reaction phenotyping for the in vitro assessment of the bioactivation of bromfenac. Chem Res Toxicol. 2020 Jan 21;33(1):249-257.
2 Metabolic disposition of 14C-bromfenac in healthy male volunteers J Clin Pharmacol. 1998 Aug;38(8):744-52. doi: 10.1002/j.1552-4604.1998.tb04815.x.

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