Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000731)
Formula Reactant Nitroso-dapsone Product Dapsone mercaptal intermediate
Reactant Info Product Info
Metabolic Type Conjugation - Glutathione Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000730 Dapsone hydroxylamine Nitroso-dapsone Oxidation - Oxidation Dapsone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000732 Dapsone mercaptal intermediate Dapsone GSH conjugate metabolite Other reaction - Spontaneous Dapsone [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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