Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000780)
Formula Reactant D3-10-O-Desmethyl-Alpha-Htbz Product Sulfate of O\desmethyl alpha\HTBZ
Reactant Info Product Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000778 D6alpha-dihydrotetrabenazine D3-10-O-Desmethyl-Alpha-Htbz Oxidation - Demethylation Deutetrabenazine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000779 D3-9-O-Desmethyl-Alpha-Htbz Sulfate of O\desmethyl alpha\HTBZ Conjugation - Sulfation Deutetrabenazine [1]
References
1 Pharmacokinetic and Metabolic Profile of Deutetrabenazine (TEV-50717) Compared With Tetrabenazine in Healthy Volunteers Clin Transl Sci. 2020 Jul;13(4):707-717. doi: 10.1111/cts.12754.

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