Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000784)
Formula Reactant D3-9-O-Desmethyl-beta-Htbz Product Sulfate of O\desmethyl beta\HTBZ
Reactant Info Product Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000781 Cis (2,3)-Dihydro Tetrabenazine-d6 D3-9-O-Desmethyl-beta-Htbz Oxidation - Demethylation Deutetrabenazine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000785 D3-10-O-Desmethyl-beta-Htbz Sulfate of O\desmethyl beta\HTBZ Conjugation - Sulfation Deutetrabenazine [1]
References
1 Pharmacokinetic and Metabolic Profile of Deutetrabenazine (TEV-50717) Compared With Tetrabenazine in Healthy Volunteers Clin Transl Sci. 2020 Jul;13(4):707-717. doi: 10.1111/cts.12754.

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