Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000850)
Formula Reactant Digoxigenin-monodigitoxoside Product DG1 glucuronidation
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronyltransferase (UGT) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000848 Digoxigenin-bisdigitoxoside Digoxigenin-monodigitoxoside Oxidation - Cleavage Digoxin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000849 Digoxigenin-monodigitoxoside Digoxigenin Oxidation - Cleavage Digoxin [2]
References
1 Metabolism of digoxin and digoxigenin digitoxosides in rat liver microsomes: involvement of cytochrome P4503A Xenobiotica. 1999 Feb;29(2):171-85. doi: 10.1080/004982599238722.
2 American Society of Health System Pharmacists; AHFS Drug Information 2010. Bethesda, MD. (2010), p. 2511

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