Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000902)
Formula	Reactant	Efavirenz metabolite M5	Product	Efavirenz metabolite M7
Formula	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	UDP-glucuronyltransferase (UGT)				DME Info
Metabolic Type	Conjugation - Conjugation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000904	Efavirenz	Efavirenz metabolite M5	Oxidation - Hydroxylation	Efavirenz	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000901	Efavirenz metabolite M5	Efavirenz metabolite M6	Conjugation - Conjugation	Efavirenz	[1]

References
1	Clinical pharmacokinetics and drug-drug interactions of Elbasvir/Grazoprevir. Eur J Drug Metab Pharmacokinet. 2018 Oct;43(5):509-531.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.