Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000949)
Formula
SVG example
Reactant Oxcarbazepine Product 10-hydroxycarbazepine glucuronide metabolite
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001871 Oxcarbazepine Eslicarbazepine Reduction - Reduction Oxcarbazepine [1]
MR001869 Oxcarbazepine Oxcarbazepine alcohol sulfate Conjugation - Sulfation Oxcarbazepine [2]
MR001870 Oxcarbazepine Oxcarbazepine glucuronide Conjugation - O-Glucuronidation Oxcarbazepine [2]
MR001872 Oxcarbazepine R-licarbazepine Reduction - Reduction Oxcarbazepine [1]
MR000948 Oxcarbazepine Eslicarbazepine Reduction - Reduction Eslicarbazepine acetate [3]
MR000947 Oxcarbazepine Oxcarbazepine alcohol sulfate Unclear Eslicarbazepine acetate [3]
MR000950 Oxcarbazepine R-licarbazepine Reduction - Reduction Eslicarbazepine acetate [3]
References
1 The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man. Chem Biol Interact. 2014 Sep 5;220:241-7.
2 The metabolism of 14C-oxcarbazepine in man Xenobiotica. 1986 Aug;16(8):769-78. doi: 10.3109/00498258609043567.
3 U. S. FDA Label -Eslicarbazepine acetate

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